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For 25 years Luke needed jabs to stop bleeding. Now he’s been liberated by a breakthrough therapy 

When Luke Pembroke was diagnosed with the bleeding disorder haemophilia at 11 months old, doctors offered his mother Debra a glimmer of hope — one day, thanks to gene therapy, there might be a cure for the inherited disorder, which made every bump and fall potentially lethal for her precious son.

It was a bold prediction in the early 1990s, when the science of gene therapy — the replacement of faulty genes with healthy ones to correct incurable genetic conditions — was in its infancy.

But fast forward nearly three decades and the prediction is coming true, bringing hope to thousands living with haemophilia in the UK. 

According to charity The Haemophilia Society, at least 16 types of gene therapy for the disorder are in development. Some are already in clinical trials and could be…


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